Feline Leukemia Virus Immunosuppression

Clinical and immunologic aspects of FeLV

Abstract Cats exposed to the feline leukemia virus (FeLV) may mount an effective immune response and eliminate the virus , develop a non-viremic, latent infection or become persistently infected and shed the virus . Persistently infected cats commonly die of secondary opportunistic infections that result from FeLV-induced immunosuppression .

A comprehensive understanding of the interconnected mechanisms governing FeLV pathogenesis—particularly those driving virus -induced immunosuppression—serves as a critical foundation for identifying therapeutic and prophylactic targets across distinct stages of host- virus interaction. Feline leukaemia virus (FeLV), a member of the Gammaretrovirus genus, remains one of the most clinically ...

Immunosuppression in a Comparative Study of Feline Leukemia Virus ...

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